RBPJ

Recombination signal binding protein for immunoglobulin kappa J region
File:PBB Protein RBPJ image.jpg PDB rendering based on 2f8x.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 2f8x​
Identifiers
Symbols	RBPJ ; CBF1; IGKJRB; IGKJRB1; KBF2; MGC61669; RBP-J; RBPJK; RBPSUH; SUH; csl
External IDs	Template:OMIM5 Template:MGI HomoloGene: 7511
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE RBPJ 211974 x at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Recombination signal binding protein for immunoglobulin kappa J region, also known as RBPJ, is a human gene.

Further reading

• Oka C, Kawaichi M (1995). "V(D)J recombination of immunoglobulin genes". Adv. Biophys. 31: 163–80. PMID 7625272.
• Matsunami N, Hamaguchi Y, Yamamoto Y; et al. (1990). "A protein binding to the J kappa recombination sequence of immunoglobulin genes contains a sequence related to the integrase motif". Nature. 342 (6252): 934–7. doi:10.1038/342934a0. PMID 2556644.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Tong X, Drapkin R, Yalamanchili R; et al. (1995). "The Epstein-Barr virus nuclear protein 2 acidic domain forms a complex with a novel cellular coactivator that can interact with TFIIE". Mol. Cell. Biol. 15 (9): 4735–44. PMID 7651391.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Amakawa R, Jing W, Ozawa K; et al. (1993). "Human Jk recombination signal binding protein gene (IGKJRB): comparison with its mouse homologue". Genomics. 17 (2): 306–15. doi:10.1006/geno.1993.1326. PMID 8406481.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zhao B, Marshall DR, Sample CE (1996). "A conserved domain of the Epstein-Barr virus nuclear antigens 3A and 3C binds to a discrete domain of Jkappa". J. Virol. 70 (7): 4228–36. PMID 8676443.CS1 maint: Multiple names: authors list (link)
• Tamura K, Taniguchi Y, Minoguchi S; et al. (1997). "Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J kappa/Su(H)". Curr. Biol. 5 (12): 1416–23. PMID 8749394.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gress TM, Müller-Pillasch F, Geng M; et al. (1996). "A pancreatic cancer-specific expression profile". Oncogene. 13 (8): 1819–30. PMID 8895530.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hsieh JJ, Nofziger DE, Weinmaster G, Hayward SD (1997). "Epstein-Barr virus immortalization: Notch2 interacts with CBF1 and blocks differentiation". J. Virol. 71 (3): 1938–45. PMID 9032325.CS1 maint: Multiple names: authors list (link)
• Aster JC, Robertson ES, Hasserjian RP; et al. (1997). "Oncogenic forms of NOTCH1 lacking either the primary binding site for RBP-Jkappa or nuclear localization sequences retain the ability to associate with RBP-Jkappa and activate transcription". J. Biol. Chem. 272 (17): 11336–43. PMID 9111040.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Tang X, Saito-Ohara F, Song J; et al. (1997). "Assignment of the human gene for KBF2/RBP-Jk to chromosome 9p12-13 and 9q13 by fluorescence in situ hybridization". Jpn. J. Hum. Genet. 42 (2): 337–41. PMID 9290259.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kao HY, Ordentlich P, Koyano-Nakagawa N; et al. (1998). "A histone deacetylase corepressor complex regulates the Notch signal transduction pathway". Genes Dev. 12 (15): 2269–77. PMID 9694793.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hsieh JJ, Zhou S, Chen L; et al. (1999). "CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex". Proc. Natl. Acad. Sci. U.S.A. 96 (1): 23–8. PMID 9874765.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Scanlan MJ, Gordan JD, Williamson B; et al. (1999). "Antigens recognized by autologous antibody in patients with renal-cell carcinoma". Int. J. Cancer. 83 (4): 456–64. PMID 10508479.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Callahan J, Aster J, Sklar J; et al. (2000). "Intracellular forms of human NOTCH1 interact at distinctly different levels with RBP-jkappa in human B and T cells". Leukemia. 14 (1): 84–92. PMID 10637481.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Smith PR, de Jesus O, Turner D; et al. (2000). "Structure and coding content of CST (BART) family RNAs of Epstein-Barr virus". J. Virol. 74 (7): 3082–92. PMID 10708423.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zhou S, Fujimuro M, Hsieh JJ; et al. (2000). "SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC function". Mol. Cell. Biol. 20 (7): 2400–10. PMID 10713164.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kurooka H, Honjo T (2000). "Functional interaction between the mouse notch1 intracellular region and histone acetyltransferases PCAF and GCN5". J. Biol. Chem. 275 (22): 17211–20. doi:10.1074/jbc.M000909200. PMID 10747963.
• Beatus P, Lundkvist J, Oberg C; et al. (2001). "The origin of the ankyrin repeat region in Notch intracellular domains is critical for regulation of HES promoter activity". Mech. Dev. 104 (1–2): 3–20. PMID 11404076.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zhou S, Hayward SD (2001). "Nuclear localization of CBF1 is regulated by interactions with the SMRT corepressor complex". Mol. Cell. Biol. 21 (18): 6222–32. PMID 11509665.

External links

• RBPJ+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.