DNA damage-inducible transcript 3

DNA-damage-inducible transcript 3
Identifiers
Symbols	DDIT3 ; CEBPZ; CHOP; CHOP10; GADD153; MGC4154
External IDs	Template:OMIM5 Template:MGI HomoloGene: 3012
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

DNA-damage-inducible transcript 3, also known as DDIT3, is a human gene.

Further reading

• Ramji DP, Foka P (2002). "CCAAT/enhancer-binding proteins: structure, function and regulation". Biochem. J. 365 (Pt 3): 561–75. doi:10.1042/BJ20020508. PMID 12006103.
• Oyadomari S, Mori M (2004). "Roles of CHOP/GADD153 in endoplasmic reticulum stress". Cell Death Differ. 11 (4): 381–9. doi:10.1038/sj.cdd.4401373. PMID 14685163.
• Aman P, Ron D, Mandahl N; et al. (1993). "Rearrangement of the transcription factor gene CHOP in myxoid liposarcomas with t(12;16)(q13;p11)". Genes Chromosomes Cancer. 5 (4): 278–85. PMID 1283316.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Park JS, Luethy JD, Wang MG; et al. (1992). "Isolation, characterization and chromosomal localization of the human GADD153 gene". Gene. 116 (2): 259–67. PMID 1339368.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ron D, Habener JF (1992). "CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription". Genes Dev. 6 (3): 439–53. PMID 1547942.
• Papathanasiou MA, Kerr NC, Robbins JH; et al. (1991). "Induction by ionizing radiation of the gadd45 gene in cultured human cells: lack of mediation by protein kinase C.". Mol. Cell. Biol. 11 (2): 1009–16. PMID 1990262.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Eneroth M, Mandahl N, Heim S; et al. (1990). "Localization of the chromosomal breakpoints of the t(12;16) in liposarcoma to subbands 12q13.3 and 16p11.2". Cancer Genet. Cytogenet. 48 (1): 101–7. PMID 2372777.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rabbitts TH, Forster A, Larson R, Nathan P (1993). "Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma". Nat. Genet. 4 (2): 175–80. doi:10.1038/ng0693-175. PMID 7503811.CS1 maint: Multiple names: authors list (link)
• Crozat A, Aman P, Mandahl N, Ron D (1993). "Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma". Nature. 363 (6430): 640–4. doi:10.1038/363640a0. PMID 8510758.CS1 maint: Multiple names: authors list (link)
• Chen BP, Wolfgang CD, Hai T (1996). "Analysis of ATF3, a transcription factor induced by physiological stresses and modulated by gadd153/Chop10". Mol. Cell. Biol. 16 (3): 1157–68. PMID 8622660.CS1 maint: Multiple names: authors list (link)
• Panagopoulos I, Höglund M, Mertens F; et al. (1996). "Fusion of the EWS and CHOP genes in myxoid liposarcoma". Oncogene. 12 (3): 489–94. PMID 8637704.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wang XZ, Ron D (1996). "Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase". Science. 272 (5266): 1347–9. PMID 8650547.
• Fawcett TW, Eastman HB, Martindale JL, Holbrook NJ (1996). "Physical and functional association between GADD153 and CCAAT/enhancer-binding protein beta during cellular stress". J. Biol. Chem. 271 (24): 14285–9. PMID 8662954.CS1 maint: Multiple names: authors list (link)
• Ubeda M, Vallejo M, Habener JF (1999). "CHOP enhancement of gene transcription by interactions with Jun/Fos AP-1 complex proteins". Mol. Cell. Biol. 19 (11): 7589–99. PMID 10523647.CS1 maint: Multiple names: authors list (link)
• Cui K, Coutts M, Stahl J, Sytkowski AJ (2000). "Novel interaction between the transcription factor CHOP (GADD153) and the ribosomal protein FTE/S3a modulates erythropoiesis". J. Biol. Chem. 275 (11): 7591–6. PMID 10713066.CS1 maint: Multiple names: authors list (link)
• Gotoh T, Oyadomari S, Mori K, Mori M (2002). "Nitric oxide-induced apoptosis in RAW 264.7 macrophages is mediated by endoplasmic reticulum stress pathway involving ATF6 and CHOP". J. Biol. Chem. 277 (14): 12343–50. doi:10.1074/jbc.M107988200. PMID 11805088.CS1 maint: Multiple names: authors list (link)
• Satoh T, Toyoda M, Hoshino H; et al. (2002). "Activation of peroxisome proliferator-activated receptor-gamma stimulates the growth arrest and DNA-damage inducible 153 gene in non-small cell lung carcinoma cells". Oncogene. 21 (14): 2171–80. doi:10.1038/sj.onc.1205279. PMID 11948400.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Qiao D, Im E, Qi W, Martinez JD (2002). "Activator protein-1 and CCAAT/enhancer-binding protein mediated GADD153 expression is involved in deoxycholic acid-induced apoptosis". Biochim. Biophys. Acta. 1583 (1): 108–16. PMID 12069855.CS1 maint: Multiple names: authors list (link)
• Talukder AH, Wang RA, Kumar R (2002). "Expression and transactivating functions of the bZIP transcription factor GADD153 in mammary epithelial cells". Oncogene. 21 (27): 4289–300. doi:10.1038/sj.onc.1205529. PMID 12082616.CS1 maint: Multiple names: authors list (link)

External links

• DDIT3+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.