ERG (gene)

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V-ets erythroblastosis virus E26 oncogene homolog (avian)
PDB rendering based on 1fli.
Available structures
PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB
Identifiers
Symbols ERG ; erg-3; p55
External IDs Template:OMIM5 Template:MGI HomoloGene: 15848
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

V-ets erythroblastosis virus E26 oncogene homolog (avian), also known as ERG, is a human gene.[1]


References

  1. ↑ "Entrez Gene: ERG v-ets erythroblastosis virus E26 oncogene homolog (avian)".

ERG stands for Ets Related Gene

Further reading

  • Rao VN, Modi WS, Drabkin HD; et al. (1990). "The human erg gene maps to chromosome 21, band q22: relationship to the 8; 21 translocation of acute myelogenous leukemia". Oncogene. 3 (5): 497–500. PMID 3274086.
  • Rao VN, Papas TS, Reddy ES (1987). "erg, a human ets-related gene on chromosome 21: alternative splicing, polyadenylation, and translation". Science. 237 (4815): 635–9. PMID 3299708.
  • Reddy ES, Rao VN, Papas TS (1987). "The erg gene: a human gene related to the ets oncogene". Proc. Natl. Acad. Sci. U.S.A. 84 (17): 6131–5. PMID 3476934.

Reddy ES, Rao VN (December 1991). "erg, an ets-related gene, codes for sequence-specific transcriptional activators". Oncogene 6 (12): 2285–9.

Siddique HR, Rao VN, Lee L, Reddy ES (July 1993). "Characterization of the DNA binding and transcriptional activation domains of the erg protein". Oncogene 8 (7): 1751–5.

Yi H, Fujimura Y, Ouchida M, Prasad DD, Rao VN, Reddy ES (March 1997). "Inhibition of apoptosis by normal and aberrant Fli-1 and erg proteins involved in human solid tumors and leukemias". Oncogene 14 (11): 1259–68.

  • Giovannini M, Biegel JA, Serra M; et al. (1994). "EWS-erg and EWS-Fli1 fusion transcripts in Ewing's sarcoma and primitive neuroectodermal tumors with variant translocations". J. Clin. Invest. 94 (2): 489–96. PMID 8040301.
  • Dunn T, Praissman L, Hagag N, Viola MV (1994). "ERG gene is translocated in an Ewing's sarcoma cell line". Cancer Genet. Cytogenet. 76 (1): 19–22. PMID 8076344.
  • Ichikawa H, Shimizu K, Hayashi Y, Ohki M (1994). "An RNA-binding protein gene, TLS/FUS, is fused to ERG in human myeloid leukemia with t(16;21) chromosomal translocation". Cancer Res. 54 (11): 2865–8. PMID 8187069.
  • Prasad DD, Rao VN, Lee L, Reddy ES (1994). "Differentially spliced erg-3 product functions as a transcriptional activator". Oncogene. 9 (2): 669–73. PMID 8290279.
  • Murakami K, Mavrothalassitis G, Bhat NK; et al. (1993). "Human ERG-2 protein is a phosphorylated DNA-binding protein--a distinct member of the ets family". Oncogene. 8 (6): 1559–66. PMID 8502479.
  • Duterque-Coquillaud M, Niel C, Plaza S, Stehelin D (1993). "New human erg isoforms generated by alternative splicing are transcriptional activators". Oncogene. 8 (7): 1865–73. PMID 8510931.
  • Basuyaux JP, Ferreira E, Stéhelin D, Butticè G (1997). "The Ets transcription factors interact with each other and with the c-Fos/c-Jun complex via distinct protein domains in a DNA-dependent and -independent manner". J. Biol. Chem. 272 (42): 26188–95. PMID 9334186.
  • Carrère S, Verger A, Flourens A; et al. (1998). "Erg proteins, transcription factors of the Ets family, form homo, heterodimers and ternary complexes via two distinct domains". Oncogene. 16 (25): 3261–8. doi:10.1038/sj.onc.1201868. PMID 9681824.
  • McLaughlin F, Ludbrook VJ, Kola I; et al. (2000). "Characterisation of the tumour necrosis factor (TNF)-(alpha) response elements in the human ICAM-2 promoter". J. Cell. Sci. 112 ( Pt 24): 4695–703. PMID 10574717.
  • Hattori M, Fujiyama A, Taylor TD; et al. (2000). "The DNA sequence of human chromosome 21". Nature. 405 (6784): 311–9. doi:10.1038/35012518. PMID 10830953.
  • Mastrangelo T, Modena P, Tornielli S; et al. (2000). "A novel zinc finger gene is fused to EWS in small round cell tumor". Oncogene. 19 (33): 3799–804. doi:10.1038/sj.onc.1203762. PMID 10949935.
  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. PMID 11076863.
  • Verger A, Buisine E, Carrère S; et al. (2001). "Identification of amino acid residues in the ETS transcription factor Erg that mediate Erg-Jun/Fos-DNA ternary complex formation". J. Biol. Chem. 276 (20): 17181–9. doi:10.1074/jbc.M010208200. PMID 11278640.
  • Yang L, Xia L, Wu DY; et al. (2002). "Molecular cloning of ESET, a novel histone H3-specific methyltransferase that interacts with ERG transcription factor". Oncogene. 21 (1): 148–52. doi:10.1038/sj.onc.1204998. PMID 11791185.
  • Mackereth CD, Schärpf M, Gentile LN, McIntosh LP (2003). "Chemical shift and secondary structure conservation of the PNT/SAM domains from the ets family of transcription factors". J. Biomol. NMR. 24 (1): 71–2. PMID 12449421.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Matsui Y, Chansky HA, Barahmand-Pour F; et al. (2003). "COL11A2 collagen gene transcription is differentially regulated by EWS/ERG sarcoma fusion protein and wild-type ERG". J. Biol. Chem. 278 (13): 11369–75. doi:10.1074/jbc.M300164200. PMID 12554743.

External links


This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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