FOXG1

Forkhead box G1B
Identifiers
Symbols	FOXG1B ; BF1; FKH2; FKHL1; FKHL4; HBF-1; HFK1; QIN
External IDs	Template:OMIM5 Template:MGI HomoloGene: 3843
Gene ontology Molecular function Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Forkhead box G1B, also known as FOXG1B, is a human gene.

This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of the brain and telencephalon.

See also

• FOX proteins

Further reading

• Li J, Chang HW, Lai E; et al. (1995). "The oncogene qin codes for a transcriptional repressor". Cancer Res. 55 (23): 5540–4. PMID 7585630.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wiese S, Murphy DB, Schlung A; et al. (1995). "The genes for human brain factor 1 and 2, members of the fork head gene family, are clustered on chromosome 14q". Biochim. Biophys. Acta. 1262 (2–3): 105–12. PMID 7599184.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Pierrou S, Hellqvist M, Samuelsson L; et al. (1994). "Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending". EMBO J. 13 (20): 5002–12. PMID 7957066.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Murphy DB, Wiese S, Burfeind P; et al. (1994). "Human brain factor 1, a new member of the fork head gene family". Genomics. 21 (3): 551–7. doi:10.1006/geno.1994.1313. PMID 7959731.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Li J, Vogt PK (1993). "The retroviral oncogene qin belongs to the transcription factor family that includes the homeotic gene fork head". Proc. Natl. Acad. Sci. U.S.A. 90 (10): 4490–4. PMID 8099441.
• Kastury K, Li J, Druck T; et al. (1994). "The human homologue of the retroviral oncogene qin maps to chromosome 14q13". Proc. Natl. Acad. Sci. U.S.A. 91 (9): 3616–8. PMID 8170957.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Huh S, Hatini V, Marcus RC; et al. (1999). "Dorsal-ventral patterning defects in the eye of BF-1-deficient mice associated with a restricted loss of shh expression". Dev. Biol. 211 (1): 53–63. doi:10.1006/dbio.1999.9303. PMID 10373304.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Dou CL, Li S, Lai E (1999). "Dual role of brain factor-1 in regulating growth and patterning of the cerebral hemispheres". Cereb. Cortex. 9 (6): 543–50. PMID 10498272.CS1 maint: Multiple names: authors list (link)
• Dou C, Lee J, Liu B; et al. (2000). "BF-1 interferes with transforming growth factor beta signaling by associating with Smad partners". Mol. Cell. Biol. 20 (17): 6201–11. PMID 10938097.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yao J, Lai E, Stifani S (2001). "The winged-helix protein brain factor 1 interacts with groucho and hes proteins to repress transcription". Mol. Cell. Biol. 21 (6): 1962–72. doi:10.1128/MCB.21.6.1962-1972.2001. PMID 11238932.CS1 maint: Multiple names: authors list (link)
• Rodriguez C, Huang LJ, Son JK; et al. (2001). "Functional cloning of the proto-oncogene brain factor-1 (BF-1) as a Smad-binding antagonist of transforming growth factor-beta signaling". J. Biol. Chem. 276 (32): 30224–30. doi:10.1074/jbc.M102759200. PMID 11387330.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Heilig R, Eckenberg R, Petit JL; et al. (2003). "The DNA sequence and analysis of human chromosome 14". Nature. 421 (6923): 601–7. doi:10.1038/nature01348. PMID 12508121.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Tan K, Shaw AL, Madsen B; et al. (2003). "Human PLU-1 Has transcriptional repression properties and interacts with the developmental transcription factors BF-1 and PAX9". J. Biol. Chem. 278 (23): 20507–13. doi:10.1074/jbc.M301994200. PMID 12657635.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Seoane J, Le HV, Shen L; et al. (2004). "Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation". Cell. 117 (2): 211–23. PMID 15084259.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Shoichet SA, Kunde SA, Viertel P; et al. (2005). "Haploinsufficiency of novel FOXG1B variants in a patient with severe mental retardation, brain malformations and microcephaly". Hum. Genet. 117 (6): 536–44. doi:10.1007/s00439-005-1310-3. PMID 16133170.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bredenkamp N, Seoighe C, Illing N (2007). "Comparative evolutionary analysis of the FoxG1 transcription factor from diverse vertebrates identifies conserved recognition sites for microRNA regulation". Dev. Genes Evol. 217 (3): 227–33. doi:10.1007/s00427-006-0128-x. PMID 17260156.CS1 maint: Multiple names: authors list (link)

External links

• FOXG1B+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.