GTF2H1

General transcription factor IIH, polypeptide 1, 62kDa
PDB rendering based on 1pfj.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1pfj​, 2dii​
Identifiers
Symbols	GTF2H1 ; BTF2; TFIIH
External IDs	Template:OMIM5 Template:MGI HomoloGene: 3885
Gene ontology Molecular function Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

General transcription factor IIH, polypeptide 1, 62kDa, also known as GTF2H1, is a human gene.

See also

• Transcription Factor II H

Further reading

• Jeang KT (1998). "Tat, Tat-associated kinase, and transcription". J. Biomed. Sci. 5 (1): 24–7. PMID 9570510.
• Yankulov K, Bentley D (1998). "Transcriptional control: Tat cofactors and transcriptional elongation". Curr. Biol. 8 (13): R447–9. PMID 9651670.
• Fischer L, Gerard M, Chalut C; et al. (1992). "Cloning of the 62-kilodalton component of basic transcription factor BTF2". Science. 257 (5075): 1392–5. PMID 1529339.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Shiekhattar R, Mermelstein F, Fisher RP; et al. (1995). "Cdk-activating kinase complex is a component of human transcription factor TFIIH". Nature. 374 (6519): 283–7. doi:10.1038/374283a0. PMID 7533895.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Tong X, Drapkin R, Reinberg D, Kieff E (1995). "The 62- and 80-kDa subunits of transcription factor IIH mediate the interaction with Epstein-Barr virus nuclear protein 2". Proc. Natl. Acad. Sci. U.S.A. 92 (8): 3259–63. PMID 7724549.CS1 maint: Multiple names: authors list (link)
• Fantes JA, Oghene K, Boyle S; et al. (1995). "A high-resolution integrated physical, cytogenetic, and genetic map of human chromosome 11: distal p13 to proximal p15.1". Genomics. 25 (2): 447–61. PMID 7789978.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Xiao H, Pearson A, Coulombe B; et al. (1994). "Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53". Mol. Cell. Biol. 14 (10): 7013–24. PMID 7935417.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Heng HH, Xiao H, Shi XM; et al. (1994). "Genes encoding general initiation factors for RNA polymerase II transcription are dispersed in the human genome". Hum. Mol. Genet. 3 (1): 61–4. PMID 8162052.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Schaeffer L, Moncollin V, Roy R; et al. (1994). "The ERCC2/DNA repair protein is associated with the class II BTF2/TFIIH transcription factor". EMBO J. 13 (10): 2388–92. PMID 8194528.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Blau J, Xiao H, McCracken S; et al. (1996). "Three functional classes of transcriptional activation domain". Mol. Cell. Biol. 16 (5): 2044–55. PMID 8628270.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Iyer N, Reagan MS, Wu KJ; et al. (1996). "Interactions involving the human RNA polymerase II transcription/nucleotide excision repair complex TFIIH, the nucleotide excision repair protein XPG, and Cockayne syndrome group B (CSB) protein". Biochemistry. 35 (7): 2157–67. doi:10.1021/bi9524124. PMID 8652557.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Reardon JT, Ge H, Gibbs E; et al. (1996). "Isolation and characterization of two human transcription factor IIH (TFIIH)-related complexes: ERCC2/CAK and TFIIH". Proc. Natl. Acad. Sci. U.S.A. 93 (13): 6482–7. PMID 8692841.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Drapkin R, Le Roy G, Cho H; et al. (1996). "Human cyclin-dependent kinase-activating kinase exists in three distinct complexes". Proc. Natl. Acad. Sci. U.S.A. 93 (13): 6488–93. PMID 8692842.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zhou Q, Sharp PA (1996). "Tat-SF1: cofactor for stimulation of transcriptional elongation by HIV-1 Tat". Science. 274 (5287): 605–10. PMID 8849451.
• Parada CA, Roeder RG (1996). "Enhanced processivity of RNA polymerase II triggered by Tat-induced phosphorylation of its carboxy-terminal domain". Nature. 384 (6607): 375–8. doi:10.1038/384375a0. PMID 8934526.
• García-Martínez LF, Ivanov D, Gaynor RB (1997). "Association of Tat with purified HIV-1 and HIV-2 transcription preinitiation complexes". J. Biol. Chem. 272 (11): 6951–8. PMID 9054383.CS1 maint: Multiple names: authors list (link)
• Marinoni JC, Roy R, Vermeulen W; et al. (1997). "Cloning and characterization of p52, the fifth subunit of the core of the transcription/DNA repair factor TFIIH". EMBO J. 16 (5): 1093–102. doi:10.1093/emboj/16.5.1093. PMID 9118947.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Cujec TP, Cho H, Maldonado E; et al. (1997). "The human immunodeficiency virus transactivator Tat interacts with the RNA polymerase II holoenzyme". Mol. Cell. Biol. 17 (4): 1817–23. PMID 9121429.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rossignol M, Kolb-Cheynel I, Egly JM (1997). "Substrate specificity of the cdk-activating kinase (CAK) is altered upon association with TFIIH". EMBO J. 16 (7): 1628–37. doi:10.1093/emboj/16.7.1628. PMID 9130708.CS1 maint: Multiple names: authors list (link)
• García-Martínez LF, Mavankal G, Neveu JM; et al. (1997). "Purification of a Tat-associated kinase reveals a TFIIH complex that modulates HIV-1 transcription". EMBO J. 16 (10): 2836–50. doi:10.1093/emboj/16.10.2836. PMID 9184228.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

External links

• GTF2H1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.