MEF2D

MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D)
File:PBB Protein MEF2D image.jpg PDB rendering based on 1c7u.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1c7u​, 1egw​
Identifiers
Symbols	MEF2D ; DKFZp686I1536
External IDs	Template:OMIM5 Template:MGI HomoloGene: 4327
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE MEF2D 203003 at tn.png
File:PBB GE MEF2D 203004 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D), also known as MEF2D, is a human gene.

See also

• Mef2

Further reading

• Breitbart RE, Liang CS, Smoot LB; et al. (1994). "A fourth human MEF2 transcription factor, hMEF2D, is an early marker of the myogenic lineage". Development. 118 (4): 1095–106. PMID 8269842.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hobson GM, Krahe R, Garcia E; et al. (1996). "Regional chromosomal assignments for four members of the MADS domain transcription enhancer factor 2 (MEF2) gene family to human chromosomes 15q26, 19p12, 5q14, and 1q12-q23". Genomics. 29 (3): 704–11. doi:10.1006/geno.1995.9007. PMID 8575763.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ornatsky OI, McDermott JC (1996). "MEF2 protein expression, DNA binding specificity and complex composition, and transcriptional activity in muscle and non-muscle cells". J. Biol. Chem. 271 (40): 24927–33. PMID 8798771.
• Yang CC, Ornatsky OI, McDermott JC; et al. (1998). "Interaction of myocyte enhancer factor 2 (MEF2) with a mitogen-activated protein kinase, ERK5/BMK1". Nucleic Acids Res. 26 (20): 4771–7. PMID 9753748.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zhao M, New L, Kravchenko VV; et al. (1999). "Regulation of the MEF2 family of transcription factors by p38". Mol. Cell. Biol. 19 (1): 21–30. PMID 9858528.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wang AH, Bertos NR, Vezmar M; et al. (1999). "HDAC4, a human histone deacetylase related to yeast HDA1, is a transcriptional corepressor". Mol. Cell. Biol. 19 (11): 7816–27. PMID 10523670.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lu J, McKinsey TA, Nicol RL, Olson EN (2000). "Signal-dependent activation of the MEF2 transcription factor by dissociation from histone deacetylases". Proc. Natl. Acad. Sci. U.S.A. 97 (8): 4070–5. doi:10.1073/pnas.080064097. PMID 10737771.CS1 maint: Multiple names: authors list (link)
• Kato Y, Zhao M, Morikawa A; et al. (2000). "Big mitogen-activated kinase regulates multiple members of the MEF2 protein family". J. Biol. Chem. 275 (24): 18534–40. doi:10.1074/jbc.M001573200. PMID 10849446.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Youn HD, Chatila TA, Liu JO (2000). "Integration of calcineurin and MEF2 signals by the coactivator p300 during T-cell apoptosis". EMBO J. 19 (16): 4323–31. doi:10.1093/emboj/19.16.4323. PMID 10944115.CS1 maint: Multiple names: authors list (link)
• Slepak TI, Webster KA, Zang J; et al. (2001). "Control of cardiac-specific transcription by p300 through myocyte enhancer factor-2D". J. Biol. Chem. 276 (10): 7575–85. doi:10.1074/jbc.M004625200. PMID 11096067.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Choi SJ, Park SY, Han TH (2001). "14-3-3tau associates with and activates the MEF2D transcription factor during muscle cell differentiation". Nucleic Acids Res. 29 (13): 2836–42. PMID 11433030.CS1 maint: Multiple names: authors list (link)
• Okamoto S, Li Z, Ju C; et al. (2002). "Dominant-interfering forms of MEF2 generated by caspase cleavage contribute to NMDA-induced neuronal apoptosis". Proc. Natl. Acad. Sci. U.S.A. 99 (6): 3974–9. doi:10.1073/pnas.022036399. PMID 11904443.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Park SY, Shin HM, Han TH (2002). "Synergistic interaction of MEF2D and Sp1 in activation of the CD14 promoter". Mol. Immunol. 39 (1–2): 25–30. PMID 12213324.CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Linseman DA, Bartley CM, Le SS; et al. (2003). "Inactivation of the myocyte enhancer factor-2 repressor histone deacetylase-5 by endogenous Ca(2+) //calmodulin-dependent kinase II promotes depolarization-mediated cerebellar granule neuron survival". J. Biol. Chem. 278 (42): 41472–81. doi:10.1074/jbc.M307245200. PMID 12896970.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Beausoleil SA, Jedrychowski M, Schwartz D; et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Grégoire S, Yang XJ (2005). "Association with class IIa histone deacetylases upregulates the sumoylation of MEF2 transcription factors". Mol. Cell. Biol. 25 (6): 2273–87. doi:10.1128/MCB.25.6.2273-2287.2005. PMID 15743823.
• Prima V, Gore L, Caires A; et al. (2005). "Cloning and functional characterization of MEF2D/DAZAP1 and DAZAP1/MEF2D fusion proteins created by a variant t(1;19)(q23;p13.3) in acute lymphoblastic leukemia". Leukemia. 19 (5): 806–13. doi:10.1038/sj.leu.2403684. PMID 15744350.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

External links

• MEF2D+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)