POU2F1

POU domain, class 2, transcription factor 1
File:PBB Protein POU2F1 image.jpg PDB rendering based on 1cqt.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1cqt​, 1e3o​, 1gt0​, 1hf0​, 1o4x​, 1oct​, 1pog​, 1pou​
Identifiers
Symbols	POU2F1 ; OCT1; OTF1
External IDs	Template:OMIM5 Template:MGI HomoloGene: 37658
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE POU2F1 206789 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

POU domain, class 2, transcription factor 1, also known as POU2F1, is a human gene.

See also

• Octamer transcription factor

Further reading

• Roberts SB, Segil N, Heintz N (1991). "Differential phosphorylation of the transcription factor Oct1 during the cell cycle". Science. 253 (5023): 1022–6. PMID 1887216.CS1 maint: Multiple names: authors list (link)
• Hsieh CL, Sturm R, Herr W, Francke U (1990). "The gene for the ubiquitous octamer-binding protein Oct-1 is on human chromosome 1, region cen-q32, and near Ly-22 and Ltw-4 on mouse chromosome 1". Genomics. 6 (4): 666–72. PMID 2341156.CS1 maint: Multiple names: authors list (link)
• Sturm RA, Das G, Herr W (1989). "The ubiquitous octamer-binding protein Oct-1 contains a POU domain with a homeo box subdomain". Genes Dev. 2 (12A): 1582–99. PMID 2905684.CS1 maint: Multiple names: authors list (link)
• Nakshatri H, Nakshatri P, Currie RA (1995). "Interaction of Oct-1 with TFIIB. Implications for a novel response elicited through the proximal octamer site of the lipoprotein lipase promoter". J. Biol. Chem. 270 (33): 19613–23. PMID 7642649.CS1 maint: Multiple names: authors list (link)
• Cox M, van Tilborg PJ, de Laat W; et al. (1995). "Solution structure of the Oct-1 POU homeodomain determined by NMR and restrained molecular dynamics". J. Biomol. NMR. 6 (1): 23–32. PMID 7663141.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Jeang KT, Chun R, Lin NH; et al. (1993). "In vitro and in vivo binding of human immunodeficiency virus type 1 Tat protein and Sp1 transcription factor". J. Virol. 67 (10): 6224–33. PMID 7690421.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zwilling S, König H, Wirth T (1995). "High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors". EMBO J. 14 (6): 1198–208. PMID 7720710.CS1 maint: Multiple names: authors list (link)
• Sturm RA, Eyre HJ, Baker E, Sutherland GR (1995). "The human OTF1 locus which overlaps the CD3Z gene is located at 1q22-->q23". Cytogenet. Cell Genet. 68 (3–4): 231–2. PMID 7842742.CS1 maint: Multiple names: authors list (link)
• Klemm JD, Rould MA, Aurora R; et al. (1994). "Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules". Cell. 77 (1): 21–32. PMID 8156594.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zwilling S, Annweiler A, Wirth T (1994). "The POU domains of the Oct1 and Oct2 transcription factors mediate specific interaction with TBP". Nucleic Acids Res. 22 (9): 1655–62. PMID 8202368.CS1 maint: Multiple names: authors list (link)
• Kristie TM, Sharp PA (1993). "Purification of the cellular C1 factor required for the stable recognition of the Oct-1 homeodomain by the herpes simplex virus alpha-trans-induction factor (VP16)". J. Biol. Chem. 268 (9): 6525–34. PMID 8454622.
• Assa-Munt N, Mortishire-Smith RJ, Aurora R; et al. (1993). "The solution structure of the Oct-1 POU-specific domain reveals a striking similarity to the bacteriophage lambda repressor DNA-binding domain". Cell. 73 (1): 193–205. PMID 8462099.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Dekker N, Cox M, Boelens R; et al. (1993). "Solution structure of the POU-specific DNA-binding domain of Oct-1". Nature. 362 (6423): 852–5. doi:10.1038/362852a0. PMID 8479524.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ström AC, Forsberg M, Lillhager P, Westin G (1996). "The transcription factors Sp1 and Oct-1 interact physically to regulate human U2 snRNA gene expression". Nucleic Acids Res. 24 (11): 1981–6. PMID 8668525.CS1 maint: Multiple names: authors list (link)
• Inamoto S, Segil N, Pan ZQ; et al. (1997). "The cyclin-dependent kinase-activating kinase (CAK) assembly factor, MAT1, targets and enhances CAK activity on the POU domains of octamer transcription factors". J. Biol. Chem. 272 (47): 29852–8. PMID 9368058.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wong MW, Henry RW, Ma B; et al. (1998). "The large subunit of basal transcription factor SNAPc is a Myb domain protein that interacts with Oct-1". Mol. Cell. Biol. 18 (1): 368–77. PMID 9418884.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nie J, Sakamoto S, Song D; et al. (1998). "Interaction of Oct-1 and automodification domain of poly(ADP-ribose) synthetase". FEBS Lett. 424 (1–2): 27–32. PMID 9537509.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Préfontaine GG, Lemieux ME, Giffin W; et al. (1998). "Recruitment of octamer transcription factors to DNA by glucocorticoid receptor". Mol. Cell. Biol. 18 (6): 3416–30. PMID 9584182.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• La Boissière S, Hughes T, O'Hare P (1999). "HCF-dependent nuclear import of VP16". EMBO J. 18 (2): 480–9. doi:10.1093/emboj/18.2.480. PMID 9889203.CS1 maint: Multiple names: authors list (link)
• Kakizawa T, Miyamoto T, Ichikawa K; et al. (1999). "Functional interaction between Oct-1 and retinoid X receptor". J. Biol. Chem. 274 (27): 19103–8. PMID 10383413.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

External links

• POU2F1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)