Estrogen related receptor

estrogen-related receptor alpha
Identifiers
Symbol	ESRRA
Alt. symbols	ESRL1
Entrez	2101
HUGO	3471
OMIM	601998
RefSeq	NM_004451
UniProt	P11474
Other data
Locus	Chr. 11 q12

estrogen-related receptor beta
Identifiers
Symbol	ESRRB
Alt. symbols	ESRL2
Entrez	2103
HUGO	3473
OMIM	602167
RefSeq	NM_004452
UniProt	O95718
Other data
Locus	Chr. 14 q24.3

estrogen-related receptor gamma
Identifiers
Symbol	ESRRG
Entrez	2104
HUGO	3474
OMIM	602969
RefSeq	NM_206595
UniProt	P62508
Other data
Locus	Chr. 1 q41

There are three known estrogen related receptors:

• ERRα (ESRRA)
• ERRβ (ESRRB)
• ERRγ (ESRRG)

The ERRs are members of the orphan nuclear receptor family.

ERR's bind to estrogen response elements on DNA and modulate transcription but do not bind to endogenous estrogens.

In addition, ERR's seem to have their own response elements termed ERRE's. ERR's have been shown to play a role in energy homeostasis and cancer.

External links

• ERRalpha+estrogen-related+receptor at the US National Library of Medicine Medical Subject Headings (MeSH)
• estrogen+receptor-related+receptor+beta at the US National Library of Medicine Medical Subject Headings (MeSH)
• ESRRB+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
• ESRRG+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)