ZBTB17: Difference between revisions

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{{Infobox_gene}}
{{PBB_Controls
'''Zinc finger and BTB domain-containing protein 17''' is a [[protein]] that in humans is encoded by the ''ZBTB17'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: ZBTB17 zinc finger and BTB domain containing 17| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7709| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Interactions ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =  
| Name = Zinc finger and BTB domain containing 17
| HGNCid = 12936
| Symbol = ZBTB17
| AltSymbols =; MIZ-1; ZNF151; pHZ-67
| OMIM = 604084
| ECnumber = 
| Homologene = 2575
| MGIid = 107410
| GeneAtlas_image1 = PBB_GE_ZBTB17_203602_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_ZBTB17_203601_s_at_tn.png
| Function = {{GNF_GO|id=GO:0003700 |text = transcription factor activity}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0008270 |text = zinc ion binding}} {{GNF_GO|id=GO:0046872 |text = metal ion binding}}
| Component = {{GNF_GO|id=GO:0005622 |text = intracellular}} {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process = {{GNF_GO|id=GO:0006350 |text = transcription}} {{GNF_GO|id=GO:0006355 |text = regulation of transcription, DNA-dependent}} {{GNF_GO|id=GO:0007275 |text = multicellular organismal development}} {{GNF_GO|id=GO:0045786 |text = negative regulation of progression through cell cycle}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 7709
    | Hs_Ensembl = ENSG00000116809
    | Hs_RefseqProtein = NP_003434
    | Hs_RefseqmRNA = NM_003443
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 1
    | Hs_GenLoc_start = 16140951
    | Hs_GenLoc_end = 16175208
    | Hs_Uniprot = Q13105
    | Mm_EntrezGene = 22642
    | Mm_Ensembl = ENSMUSG00000006215
    | Mm_RefseqmRNA = NM_009541
    | Mm_RefseqProtein = NP_033567
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 4
    | Mm_GenLoc_start = 140716760
    | Mm_GenLoc_end = 140740006
    | Mm_Uniprot = Q6PAT9
  }}
}}
'''Zinc finger and BTB domain containing 17''', also known as '''ZBTB17''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: ZBTB17 zinc finger and BTB domain containing 17| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7709| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
ZBTB17 has been shown to [[Protein-protein interaction|interact]] with [[TOPBP1]],<ref name=pmid12408820>{{cite journal | vauthors = Herold S, Wanzel M, Beuger V, Frohme C, Beul D, Hillukkala T, Syvaoja J, Saluz HP, Haenel F, Eilers M | title = Negative regulation of the mammalian UV response by Myc through association with Miz-1 | journal = Molecular Cell | volume = 10 | issue = 3 | pages = 509–21 | date = Sep 2002 | pmid = 12408820 | doi = 10.1016/S1097-2765(02)00633-0 }}</ref> [[Host cell factor C1]]<ref name=pmid12244100>{{cite journal | vauthors = Piluso D, Bilan P, Capone JP | title = Host cell factor-1 interacts with and antagonizes transactivation by the cell cycle regulatory factor Miz-1 | journal = The Journal of Biological Chemistry | volume = 277 | issue = 48 | pages = 46799–808 | date = Nov 2002 | pmid = 12244100 | doi = 10.1074/jbc.M206226200 }}</ref> and [[Myc]].<ref name=pmid11283613>{{cite journal | vauthors = Staller P, Peukert K, Kiermaier A, Seoane J, Lukas J, Karsunky H, Möröy T, Bartek J, Massagué J, Hänel F, Eilers M | title = Repression of p15INK4b expression by Myc through association with Miz-1 | journal = Nature Cell Biology | volume = 3 | issue = 4 | pages = 392–9 | date = Apr 2001 | pmid = 11283613 | doi = 10.1038/35070076 }}</ref><ref name=pmid9312026>{{cite journal | vauthors = Peukert K, Staller P, Schneider A, Carmichael G, Hänel F, Eilers M | title = An alternative pathway for gene regulation by Myc | journal = The EMBO Journal | volume = 16 | issue = 18 | pages = 5672–86 | date = Sep 1997 | pmid = 9312026 | pmc = 1170199 | doi = 10.1093/emboj/16.18.5672 }}</ref>
{{PBB_Summary
| section_title =  
| summary_text =  
}}


==References==
== References ==
{{reflist|2}}
{{Reflist}}
==Further reading==
 
{{refbegin | 2}}
== Further reading ==
{{PBB_Further_reading
{{Refbegin | 2}}
| citations =
* {{cite journal | vauthors = Lichter P, Bray P, Ried T, Dawid IB, Ward DC | title = Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes | journal = Genomics | volume = 13 | issue = 4 | pages = 999–1007 | date = Aug 1992 | pmid = 1505991 | doi = 10.1016/0888-7543(92)90013-I }}
*{{cite journal | author=Lichter P, Bray P, Ried T, ''et al.'' |title=Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes. |journal=Genomics |volume=13 |issue= 4 |pages= 999-1007 |year= 1992 |pmid= 1505991 |doi= }}
* {{cite journal | vauthors = Bray P, Lichter P, Thiesen HJ, Ward DC, Dawid IB | title = Characterization and mapping of human genes encoding zinc finger proteins | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 88 | issue = 21 | pages = 9563–7 | date = Nov 1991 | pmid = 1946370 | pmc = 52758 | doi = 10.1073/pnas.88.21.9563 }}
*{{cite journal | author=Bray P, Lichter P, Thiesen HJ, ''et al.'' |title=Characterization and mapping of human genes encoding zinc finger proteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=88 |issue= 21 |pages= 9563-7 |year= 1991 |pmid= 1946370 |doi= }}
* {{cite journal | vauthors = Tommerup N, Vissing H | title = Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders | journal = Genomics | volume = 27 | issue = 2 | pages = 259–64 | date = May 1995 | pmid = 7557990 | doi = 10.1006/geno.1995.1040 }}
*{{cite journal | author=Tommerup N, Vissing H |title=Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders. |journal=Genomics |volume=27 |issue= 2 |pages= 259-64 |year= 1995 |pmid= 7557990 |doi= 10.1006/geno.1995.1040 }}
* {{cite journal | vauthors = Maruyama K, Sugano S | title = Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides | journal = Gene | volume = 138 | issue = 1-2 | pages = 171–4 | date = Jan 1994 | pmid = 8125298 | doi = 10.1016/0378-1119(94)90802-8 }}
*{{cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi= }}
* {{cite journal | vauthors = Wu L, Wu H, Ma L, Sangiorgi F, Wu N, Bell JR, Lyons GE, Maxson R | title = Miz1, a novel zinc finger transcription factor that interacts with Msx2 and enhances its affinity for DNA | journal = Mechanisms of Development | volume = 65 | issue = 1-2 | pages = 3–17 | date = Jul 1997 | pmid = 9256341 | doi = 10.1016/S0925-4773(97)00032-4 }}
*{{cite journal | author=Wu L, Wu H, Ma L, ''et al.'' |title=Miz1, a novel zinc finger transcription factor that interacts with Msx2 and enhances its affinity for DNA. |journal=Mech. Dev. |volume=65 |issue= 1-2 |pages= 3-17 |year= 1997 |pmid= 9256341 |doi= }}
* {{cite journal | vauthors = Schneider A, Peukert K, Eilers M, Hänel F | title = Association of Myc with the zinc-finger protein Miz-1 defines a novel pathway for gene regulation by Myc | journal = Current Topics in Microbiology and Immunology | volume = 224 | issue =  | pages = 137–46 | year = 1997 | pmid = 9308237 | doi = 10.1007/978-3-642-60801-8_14 }}
*{{cite journal | author=Schneider A, Peukert K, Eilers M, Hänel F |title=Association of Myc with the zinc-finger protein Miz-1 defines a novel pathway for gene regulation by Myc. |journal=Curr. Top. Microbiol. Immunol. |volume=224 |issue=  |pages= 137-46 |year= 1997 |pmid= 9308237 |doi= }}
* {{cite journal | vauthors = Peukert K, Staller P, Schneider A, Carmichael G, Hänel F, Eilers M | title = An alternative pathway for gene regulation by Myc | journal = The EMBO Journal | volume = 16 | issue = 18 | pages = 5672–86 | date = Sep 1997 | pmid = 9312026 | pmc = 1170199 | doi = 10.1093/emboj/16.18.5672 }}
*{{cite journal | author=Peukert K, Staller P, Schneider A, ''et al.'' |title=An alternative pathway for gene regulation by Myc. |journal=EMBO J. |volume=16 |issue= 18 |pages= 5672-86 |year= 1997 |pmid= 9312026 |doi= 10.1093/emboj/16.18.5672 }}
* {{cite journal | vauthors = Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S | title = Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library | journal = Gene | volume = 200 | issue = 1-2 | pages = 149–56 | date = Oct 1997 | pmid = 9373149 | doi = 10.1016/S0378-1119(97)00411-3 }}
*{{cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi= }}
* {{cite journal | vauthors = Sui D, Wilson JE | title = Interaction of insulin-like growth factor binding protein-4, Miz-1, leptin, lipocalin-type prostaglandin D synthase, and granulin precursor with the N-terminal half of type III hexokinase | journal = Archives of Biochemistry and Biophysics | volume = 382 | issue = 2 | pages = 262–74 | date = Oct 2000 | pmid = 11068878 | doi = 10.1006/abbi.2000.2019 }}
*{{cite journal | author=Sui D, Wilson JE |title=Interaction of insulin-like growth factor binding protein-4, Miz-1, leptin, lipocalin-type prostaglandin D synthase, and granulin precursor with the N-terminal half of type III hexokinase. |journal=Arch. Biochem. Biophys. |volume=382 |issue= 2 |pages= 262-74 |year= 2000 |pmid= 11068878 |doi= 10.1006/abbi.2000.2019 }}
* {{cite journal | vauthors = Staller P, Peukert K, Kiermaier A, Seoane J, Lukas J, Karsunky H, Möröy T, Bartek J, Massagué J, Hänel F, Eilers M | title = Repression of p15INK4b expression by Myc through association with Miz-1 | journal = Nature Cell Biology | volume = 3 | issue = 4 | pages = 392–9 | date = Apr 2001 | pmid = 11283613 | doi = 10.1038/35070076 }}
*{{cite journal | author=Staller P, Peukert K, Kiermaier A, ''et al.'' |title=Repression of p15INK4b expression by Myc through association with Miz-1. |journal=Nat. Cell Biol. |volume=3 |issue= 4 |pages= 392-9 |year= 2001 |pmid= 11283613 |doi= 10.1038/35070076 }}
* {{cite journal | vauthors = Ziegelbauer J, Shan B, Yager D, Larabell C, Hoffmann B, Tjian R | title = Transcription factor MIZ-1 is regulated via microtubule association | journal = Molecular Cell | volume = 8 | issue = 2 | pages = 339–49 | date = Aug 2001 | pmid = 11545736 | doi = 10.1016/S1097-2765(01)00313-6 }}
*{{cite journal | author=Ziegelbauer J, Shan B, Yager D, ''et al.'' |title=Transcription factor MIZ-1 is regulated via microtubule association. |journal=Mol. Cell |volume=8 |issue= 2 |pages= 339-49 |year= 2001 |pmid= 11545736 |doi= }}
* {{cite journal | vauthors = Tussie-Luna MI, Michel B, Hakre S, Roy AL | title = The SUMO ubiquitin-protein isopeptide ligase family member Miz1/PIASxbeta /Siz2 is a transcriptional cofactor for TFII-I | journal = The Journal of Biological Chemistry | volume = 277 | issue = 45 | pages = 43185–93 | date = Nov 2002 | pmid = 12193603 | doi = 10.1074/jbc.M207635200 }}
*{{cite journal | author=Tussie-Luna MI, Michel B, Hakre S, Roy AL |title=The SUMO ubiquitin-protein isopeptide ligase family member Miz1/PIASxbeta /Siz2 is a transcriptional cofactor for TFII-I. |journal=J. Biol. Chem. |volume=277 |issue= 45 |pages= 43185-93 |year= 2003 |pmid= 12193603 |doi= 10.1074/jbc.M207635200 }}
* {{cite journal | vauthors = Piluso D, Bilan P, Capone JP | title = Host cell factor-1 interacts with and antagonizes transactivation by the cell cycle regulatory factor Miz-1 | journal = The Journal of Biological Chemistry | volume = 277 | issue = 48 | pages = 46799–808 | date = Nov 2002 | pmid = 12244100 | doi = 10.1074/jbc.M206226200 }}
*{{cite journal | author=Piluso D, Bilan P, Capone JP |title=Host cell factor-1 interacts with and antagonizes transactivation by the cell cycle regulatory factor Miz-1. |journal=J. Biol. Chem. |volume=277 |issue= 48 |pages= 46799-808 |year= 2003 |pmid= 12244100 |doi= 10.1074/jbc.M206226200 }}
* {{cite journal | vauthors = Zhang H, Li Z, Viklund EK, Strömblad S | title = P21-activated kinase 4 interacts with integrin alpha v beta 5 and regulates alpha v beta 5-mediated cell migration | journal = The Journal of Cell Biology | volume = 158 | issue = 7 | pages = 1287–97 | date = Sep 2002 | pmid = 12356872 | pmc = 2173231 | doi = 10.1083/jcb.200207008 }}
*{{cite journal | author=Zhang H, Li Z, Viklund EK, Strömblad S |title=P21-activated kinase 4 interacts with integrin alpha v beta 5 and regulates alpha v beta 5-mediated cell migration. |journal=J. Cell Biol. |volume=158 |issue= 7 |pages= 1287-97 |year= 2002 |pmid= 12356872 |doi= }}
* {{cite journal | vauthors = Herold S, Wanzel M, Beuger V, Frohme C, Beul D, Hillukkala T, Syvaoja J, Saluz HP, Haenel F, Eilers M | title = Negative regulation of the mammalian UV response by Myc through association with Miz-1 | journal = Molecular Cell | volume = 10 | issue = 3 | pages = 509–21 | date = Sep 2002 | pmid = 12408820 | doi = 10.1016/S1097-2765(02)00633-0 }}
*{{cite journal | author=Herold S, Wanzel M, Beuger V, ''et al.'' |title=Negative regulation of the mammalian UV response by Myc through association with Miz-1. |journal=Mol. Cell |volume=10 |issue= 3 |pages= 509-21 |year= 2002 |pmid= 12408820 |doi= }}
* {{cite journal | vauthors = Wu S, Cetinkaya C, Munoz-Alonso MJ, von der Lehr N, Bahram F, Beuger V, Eilers M, Leon J, Larsson LG | title = Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoter | journal = Oncogene | volume = 22 | issue = 3 | pages = 351–60 | date = Jan 2003 | pmid = 12545156 | doi = 10.1038/sj.onc.1206145 }}
*{{cite journal | author=Wu S, Cetinkaya C, Munoz-Alonso MJ, ''et al.'' |title=Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoter. |journal=Oncogene |volume=22 |issue= 3 |pages= 351-60 |year= 2003 |pmid= 12545156 |doi= 10.1038/sj.onc.1206145 }}
* {{cite journal | vauthors = Bowen H, Lapham A, Phillips E, Yeung I, Alter-Koltunoff M, Levi BZ, Perry VH, Mann DA, Barton CH | title = Characterization of the murine Nramp1 promoter: requirements for transactivation by Miz-1 | journal = The Journal of Biological Chemistry | volume = 278 | issue = 38 | pages = 36017–26 | date = Sep 2003 | pmid = 12840021 | doi = 10.1074/jbc.M304301200 }}
*{{cite journal | author=Bowen H, Lapham A, Phillips E, ''et al.'' |title=Characterization of the murine Nramp1 promoter: requirements for transactivation by Miz-1. |journal=J. Biol. Chem. |volume=278 |issue= 38 |pages= 36017-26 |year= 2003 |pmid= 12840021 |doi= 10.1074/jbc.M304301200 }}
* {{cite journal | vauthors = Sakurai T, Itoh K, Higashitsuji H, Nagao T, Nonoguchi K, Chiba T, Fujita J | title = A cleaved form of MAGE-A4 binds to Miz-1 and induces apoptosis in human cells | journal = The Journal of Biological Chemistry | volume = 279 | issue = 15 | pages = 15505–14 | date = Apr 2004 | pmid = 14739298 | doi = 10.1074/jbc.M310437200 }}
*{{cite journal | author=Sakurai T, Itoh K, Higashitsuji H, ''et al.'' |title=A cleaved form of MAGE-A4 binds to Miz-1 and induces apoptosis in human cells. |journal=J. Biol. Chem. |volume=279 |issue= 15 |pages= 15505-14 |year= 2004 |pmid= 14739298 |doi= 10.1074/jbc.M310437200 }}
* {{cite journal | vauthors = Lehner B, Sanderson CM | title = A protein interaction framework for human mRNA degradation | journal = Genome Research | volume = 14 | issue = 7 | pages = 1315–23 | date = Jul 2004 | pmid = 15231747 | pmc = 442147 | doi = 10.1101/gr.2122004 }}
*{{cite journal | author=Lehner B, Sanderson CM |title=A protein interaction framework for human mRNA degradation. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1315-23 |year= 2004 |pmid= 15231747 |doi= 10.1101/gr.2122004 }}
{{Refend}}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
}}
{{refend}}


== External links ==
== External links ==
* {{MeshName|ZBTB17+protein,+human}}
* {{MeshName|ZBTB17+protein,+human}}


{{NLM content}}
{{Transcription factors|g2}}


{{protein-stub}}
{{NLM content}}
{{Transcription factors}}
[[Category:Transcription factors]]
[[Category:Transcription factors]]
{{WikiDoc Sources}}
 
 
{{Gene-1-stub}}

Latest revision as of 01:04, 19 September 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Zinc finger and BTB domain-containing protein 17 is a protein that in humans is encoded by the ZBTB17 gene.[1]

Interactions

ZBTB17 has been shown to interact with TOPBP1,[2] Host cell factor C1[3] and Myc.[4][5]

References

  1. "Entrez Gene: ZBTB17 zinc finger and BTB domain containing 17".
  2. Herold S, Wanzel M, Beuger V, Frohme C, Beul D, Hillukkala T, Syvaoja J, Saluz HP, Haenel F, Eilers M (Sep 2002). "Negative regulation of the mammalian UV response by Myc through association with Miz-1". Molecular Cell. 10 (3): 509–21. doi:10.1016/S1097-2765(02)00633-0. PMID 12408820.
  3. Piluso D, Bilan P, Capone JP (Nov 2002). "Host cell factor-1 interacts with and antagonizes transactivation by the cell cycle regulatory factor Miz-1". The Journal of Biological Chemistry. 277 (48): 46799–808. doi:10.1074/jbc.M206226200. PMID 12244100.
  4. Staller P, Peukert K, Kiermaier A, Seoane J, Lukas J, Karsunky H, Möröy T, Bartek J, Massagué J, Hänel F, Eilers M (Apr 2001). "Repression of p15INK4b expression by Myc through association with Miz-1". Nature Cell Biology. 3 (4): 392–9. doi:10.1038/35070076. PMID 11283613.
  5. Peukert K, Staller P, Schneider A, Carmichael G, Hänel F, Eilers M (Sep 1997). "An alternative pathway for gene regulation by Myc". The EMBO Journal. 16 (18): 5672–86. doi:10.1093/emboj/16.18.5672. PMC 1170199. PMID 9312026.

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.